Lowering blood pressure can reduce the risk of strokes and heart attacks. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. information submitted for this request. Spironolactone is a type of drug called an aldosterone antagonist. Dizziness, lightheadedness, or fainting may also occur, especially when you get up suddenly from a lying or sitting position. And this can sometimes lead to weight loss. This is super old- but Pepsid caused me to have multiple panic attacks a day. Do not take other medicines unless they have been discussed with your doctor. But if they become more severe or dont go away, talk with your doctor or pharmacist. privacy practices. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. However, the dose is usually not more than 100 mg per day. * Sex and gender exist on spectrums. Also, you may experience symptoms such as mood swings, headache, tiredness, sleep changes, and brief feelings similar to electric shock. And sweating can be a withdrawal symptom after you stop taking them. for long-term management of symptoms in people with: adrenal adenoma (a type of noncancerous tumor on the adrenal gland that produces aldosterone), when surgery isnt possible, bilateral micro or macronodular adrenal hyperplasia (lumps on the adrenal glands that cause the adrenal glands to grow and produce more hormones than usual). Spironolactone is a commonly used antiandrogen, especially in women who are not sexually active or have contraindications to hormonal contraceptives. If your doctor prescribes spironolactone for acne, follow their instructions regarding the dosage to take. Safety and efficacy have not been established. Off-label drug use means a drug is used for a purpose other than what its been approved for by the FDA. Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Youll also have blood tests to check your potassium level on a regular basis while youre taking spironolactone. The presence of other medical problems may affect the use of this medicine. If you have symptoms of hyperkalemia at any time while youre taking spironolactone, see your doctor right away. They can check to see if the medication or something else is causing you to lose weight. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Could time-restricted eating cause fertility problems? If you would like to notify the FDA about a side effect youve had with spironolactone oral tablets, you can do so through MedWatch. Of course, terminal phase half-lives may be longer, especially if you have severe kidney problems. This helps prevent others, including children and pets, from taking the drug by accident. You can develop hyponatremia with spironolactone because the medication makes your kidneys filter more sodium out of your body. Retrospective analysis of 63 women with hyperandrogenic skin symptoms due to polycystic ovary syndrome (PCOS), treated with spironolactone for at least 6 months as first-line treatment. Using these medicines together may cause serious unwanted effects. constipation *. other information we have about you. Sabbadin C, Saccardi C, Andrisani A, Vitagliano A, Marin L, Ragazzi E, Bordin L, Ambrosini G, Armanini D. Int J Mol Sci. However, elderly patients are more likely to have age-related kidney problems, which may require caution for patients receiving spironolactone. Suck on sugarless, hard candy whenever you are nauseous. See the Spironolactone interactions section below to read more about this. All rights reserved. But potassium-sparing diuretics, including spironolactone, help your body get rid of fluid without losing too much potassium. How long a medication remains good to use can depend on many factors, including how and where you store the medication. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. There arent any other herbs or supplements that have been specifically reported to interact with spironolactone oral tablets. Ritonavir is a tremendous inhibitor of one of the main metabolic enzymes . These conditions may cause you to lose too much water or salt and may lead to low blood pressure. If your potassium level increases too much, your doctor may lower your dosage to 25 mg taken once every other day. Different interactions can cause different effects. Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction, hyperkalemia (high levels of potassium in the blood), and numbness. Specifically, spironolactone belongs to a class of drugs called aldosterone antagonists. If you notice any other effects, check with your healthcare professional. government site. Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Drug information provided by: Merative, Micromedex. If you have weight gain with spironolactone, talk with your doctor. Spironolactone oral tablets are approved for primary hyperaldosteronism in the following situations: Spironolactone is an effective treatment for primary hyperaldosteronism. Spironolactone comes as an oral tablet and belongs to the diuretic drug class. Your doctor may also have you stop taking spironolactone temporarily. 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. This helps to treat edema (fluid retention and swelling). This can block your pores and lead to acne. Use of the terms male and female in this article refers to sex assigned at birth. Symptoms of spironolactone oral tablet overdose can include: If you think youve taken too much of this drug, call your doctor. These symptoms include: Doctors use the NYHA scale to describe the severity of heart failure symptoms. Before approving coverage for spironolactone oral tablets, your insurance company may require you to get prior authorization. Always follow your doctors instructions for your dosage. If you have symptoms of hyponatremia, see your doctor right away. Specifically, the AHA recommends these drugs be used in people with blood pressure thats: Many people need to take more than one medication to lower their blood pressure. If you have hyponatremia, your doctor may reduce your dose of spironolactone until your sodium level returns to normal. Its not known how often this side effect occurs. Keep in mind that you may be able to get a 90-day supply of spironolactone oral tablets. I have a high co-pay, and I'm over it. 1. Here are answers to some frequently asked questions about spironolactone oral tablets. The site is secure. Spironolactone shouldnt usually be taken during pregnancy, unless theres no suitable alternative treatment to be used. But when you stop taking spironolactone it will quickly stop working to manage your condition. Your doctor may need to increase your dosage of the drug or switch you to another medication. Because of this, there's a risk of serotonin syndrome. A generic drug is an exact copy of the active drug in a brand-name medication. Doing so helps to lower your blood pressure and increase your potassium level before the surgery. Aldactone is a brand-name version of spironolactone oral tablets. Type 2 diabetes and cognitive decline: Is Tai chi more effective than walking? The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Note: Some of the drugs listed here are used off-label to treat these specific conditions. bloating *. The symptoms of acid rebound include acid reflux, heartburn, regurgitation, and indigestion. Talk with your healthcare provider if you experience bothersome acid rebound . These symptoms can include muscle weakness, fatigue, nausea, vomiting, tingling, trouble breathing, heart palpitations, irregular heartbeats, and chest pain. This lowers your blood pressure and increases your potassium level. These medications are also sometimes called water pills because they help your body to get rid of excess fluid through your urine. Accessibility You can also call the American Association of Poison Control Centers at 800-222-1222 or use its online tool. Considering the half-life of this drug is around 3.5 hours and that it takes roughly 5 half-lives to clear a drug from the body, famotidine may stay in your system for up to 17.5 hours. your proxy appears to only use http and not https try changing your proxy url to be http. Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome. Portions of this document last updated: April 01, 2023. The insurance company will review the prior authorization request and decide if the drug will be covered. Note: The Food and Drug Administration (FDA) tracks side effects of drugs it has approved. diuretics other than spironolactone, such as: aldosterone antagonists other than spironolactone, such as: diuretics, other than spironolactone, such as: medications for high blood pressure, such as. Symptoms of low blood pressure can include: If you have symptoms of dehydration or low blood pressure while youre taking spironolactone, see your doctor right away. It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and to decide if you should continue to take it. Weight loss/gain The medication is also available as the brand-name drug Aldactone. Theyre recommended as an add-on treatment option for high blood pressure thats not well-managed by other drugs. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS, AMERICAN COLLEGE OF ENDOCRINOLOGY, AND ANDROGEN EXCESS AND PCOS SOCIETY DISEASE STATE CLINICAL REVIEW: GUIDE TO THE BEST PRACTICES IN THE EVALUATION AND TREATMENT OF POLYCYSTIC OVARY SYNDROME--PART 1. But if your potassium level is very high, symptoms may include: Your doctor will typically check your potassium level in the week after you start treatment with spironolactone. Your doctor may adjust your dose as needed. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather. In people with these conditions, spironolactone treats edema by helping your body to get rid of excess fluid in your urine. sharing sensitive information, make sure youre on a federal Would you like email updates of new search results? It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. In guidelines from the American Academy of Dermatology, this drug is recommended as an acne treatment option for certain females. It is used after a heart attack to improve the chance of . https://www.mayoclinic.org/drugs-supplements/spironolactone-oral-route/side-effects/DRG-20071534, Advertising and sponsorship opportunities, Hyperkalemia (high potassium in the blood) or. Will quickly stop working to manage your condition have blood tests to check your potassium level on federal... 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