Taking garlic by mouth can also modestly reduce blood pressure (12). The impact of garlic on lipid parameters: a systematic review and meta-analysis. Clin Nutr. View abstract. 131,3s (2001): 1109S-13S. Immediate allergy due to raw garlic (Allium sativum L.). Eming, S. A., Piontek, J. O., Hunzelmann, N., Rasokat, H., and Scharffetter-Kachanek, K. Severe toxic contact dermatitis caused by garlic. J Pharm Pharmacol 1997;49:908-11. View abstract. View abstract. Taking garlic along with medications that also slow blood clotting might increase the risk of bruising and bleeding. However, it is much more likely that you will want to stop eating garlic well before reaching this threshold. Atherosclerosis 1998;139:333-9. View abstract. Cancer Immunol.Immunother. View abstract. Cancer 6-1-1993;71(11):3575-3581. View abstract. Identification of the allergens: the role of mono-, di-, and trisulfides present in garlic. Lipids Health Dis. View abstract. Further research is needed to understand the effects on humans. Ried, K et al. Contact Dermatitis 2006;55(3):193-194. 2002;132(4):773-778. View abstract. *Percent Daily Values are based on a 2,000 calorie diet. Bespalov, V. G., Barash, N. I., Ivanova, O. Banerjee, Sanjay K, and Subir K Maulik. Effect of raw versus boiled garlic extract on the synthesis of prostanoids. Anything in excess can be unhealthy and harmful for you, and so is garlic. View abstract. Byrne, D. J., Neil, H. A., Vallance, D. T., and Winder, A. F. A pilot study of garlic consumption shows no significant effect on markers of oxidation or sub-fraction composition of low-density lipoprotein including lipoprotein(a) after allowance for non-compliance and the placebo effect. Toxicol.Appl.Pharmacol. Das, I., Patel, S., and Sooranna, S. R. Effects of aspirin and garlic on cyclooxygenase-induced chemiluminescence in human term placenta. View abstract. View abstract. Jalloh MA, Gregory PJ, Hein D, et al. View abstract. View abstract. Soleimani D, Parisa Moosavian S, Zolfaghari H, Paknahad Z. Kim, Hanseul et al. Taking garlic by mouth seems to reduce systolic blood pressure (the top number) by about 7-9 mmHg and, A digestive tract infection that can lead to ulcers (. Cavagnaro PF, Camargo A, Galmarini CR, Simon PW. How much garlic is toxic? Gadkari JV, Joshi VD. Diabetes Obes.Metab 2011;13(4):289-301. J Nutr. Eguchi, A., Murakami, A., and Ohigashi, H. Novel bioassay system for evaluating anti-oxidative activities of food items: use of basolateral media from differentiated Caco-2 cells. Toxicology 1999;132:215-25. Chu, T. C., Han, P., Han, G., and Potter, D. E. Intraocular pressure lowering by S-allylmercaptocysteine in rabbits. View abstract. There is, however, a downside to every coin, and excessive garlic consumption can be detrimental to health. Adler A, Holub BJ. Read more: Which Is Healthier, Raw or Cooked Garlic? Ashraf, M. Z., Hussain, M. E., and Fahim, M. Endothelium mediated vasorelaxant response of garlic in isolated rat aorta: role of nitric oxide. View abstract. While its a well-known fact that consuming too much garlic gives you bad breath, there are other side effects that most people may not know about. Researchers believe red blood cells turn the Activities of Garlic Oil, Garlic Powder, and Their Diallyl Constituents against Helicobacter pylori. View abstract. Joint pain, discomfort or swelling, especially after an injury. 24,3 (1991): 193-6. Garlic has been used safely in research for up to 7 years. Diet and other risk factors for laryngeal cancer in Shanghai, China. J Nutr 2001;131(3s):1106S-1108S. View abstract. View abstract. View abstract. Sunter WH. View abstract. Ambati, S., Yang, J. Y., Rayalam, S., Park, H. J., Della-Fera, M. A., and Baile, C. A. Ajoene exerts potent effects in 3T3-L1 adipocytes by inhibiting adipogenesis and inducing apoptosis. Contact Dermatitis 1979;5(4):274-275. 2020;72(5):791-800. Coughing up blood. Saleem, S., Ahmad, M., Ahmad, A. S., Yousuf, S., Ansari, M. A., Khan, M. B., Ishrat, T., and Islam, F. Behavioral and histologic neuroprotection of aqueous garlic extract after reversible focal cerebral ischemia. Gebhardt R, Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. View abstract. Indian J Physiol Pharmacol 1979;23(3):211-214. View abstract. Nutrition 2006;22(3):266-274. 2004;92(4):701-706. Clin Cancer Res 2006;12:4636-40. Pharmaceutical Care and Research (Yaoxue Fuwu Yu Yanjiu) (CHINA) 2002;2:122-124. It's a good idea to look for supplements that are coated (enteric coating) so they will dissolve in the intestine and not in the stomach. Although garlic is a healthy addition to a balanced diet, eating too much may cause several side effects. One of the most serious side effects of eating too much garlic is an increased risk of bleeding, especially if youre taking blood thinners or undergoing surgery. BMC Complement Med Ther. View abstract. View abstract. Effects of Allium sativum (garlic) on systolic and diastolic blood pressure in patients with essential hypertension. 2015. View abstract. Eating too much garlic can cause bad breath, also known as halitosis, especially when eaten raw. Lipids 1983;18:343-348. View abstract. Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion. Pedraza-Chaverr, Jos, et al. There is no research to state the same. View abstract. 2007;14(7-8):447-451. J Med Assoc Thai. A., Prianishnikov, V. V., Kunnova, L. M., Rabinovich, E. A., and Orekhov, A. N. [Allicor efficacy in lowering the risk of ischemic heart disease in primary prophylaxis]. J Epidemiol 1999;9:297-305. Garcia-Anoveros, J. and Nagata, K. TRPA1. Bimmermann A, Weingart K, and Schwartzkopff W. Allium sativum: Studie zur Wirksamkeit bei Hyperlipoproteinamie. Cancer Epidemiol. Daily supplementation with aged garlic extract, but not raw garlic, protects low density lipoprotein against in vitro oxidation. 8,8 343. 2020;19(2):1468-1471. Fortschr.Med 12-20-1990;108(36):703-706. View abstract. View abstract. Fleischauer AT, Poole C, Arab L. Garlic consumption and cancer prevention: meta-analyses of colorectal and stomach cancers. Arzneimittelforschung 1992;42:1473-7. View abstract. First things first amongst the mildest side effects of eating garlic is its unpleasant smell which can certainly lead to bad breath similar to onions. 2. Body Odor & Sweating Is Common. With larger consumption, a strong embarrassing smell can be observed upon sweating during warmer months. Life Sci. Rev Hosp.Clin Fac.Med Sao Paulo 1990;45(5):213-215. Garlic is one of those foods that people love to eat Nutr.Cancer 2000;38(2):245-254. Koushki M, Amiri-Dashatan N, Pourfarjam Y, Doustimotlagh AH. McCrindle BW, Helden E, and Conner WT. 2018 Mar 23. Moosavian SP, Paknahad Z, Habibagahi Z, Maracy M. The effects of garlic (Allium sativum) supplementation on inflammatory biomarkers, fatigue, and clinical symptoms in patients with active rheumatoid arthritis: A randomized, double-blind, placebo-controlled trial. Instead, eat what you can tolerate and avoid garlic supplements, as they may not have the effect that you are hoping for. Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study. View abstract. Sheela CG, Kumud K, Augusti KT. Postgrad Med J. Arch Pediatr Adolesc Med 1998;152:1089-94. While the NCCIH doesn't suggest an upper limit of garlic consumption, it does note that side effects may exist from eating raw garlic such as an upset stomach. Contact Dermatitis 2000;42:108-9. View abstract. Kim H, Keum N, Giovannucci EL, Fuchs CS, Bao Y. Garlic intake and gastric cancer risk: results from two large prospective US cohort studies. J Nat Toxins. National Center for Complementary and Integrated Health, Advantages and Disadvantages of Eating Garlic. View abstract. Balasenthil, S., Ramachandran, C. R., and Nagini, S. Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic. Atherosclerosis 1999;144:237-49. Garlic (Allium sativumL.): A Brief Review of Its Antigenotoxic Effects.Foods (Basel, Switzerland)vol. Clin Experiment Ophthalmol 2002;30:303-4. View abstract. 2004;134(1):149-152. Makheja, A. N. and Bailey, J. M. Antiplatelet constituents of garlic and onion. View abstract. According to Primary Care, garlic can weaken the "tone" of these LES muscles and cause more heartburn, especially for those with GERD or related struggles. Zeng T, Guo FF, Zhang CL, et al. View abstract. J.Dermatol. Hu, J., Nyren, O., Wolk, A., Bergstrom, R., Yuen, J., Adami, H. O., Guo, L., Li, H., Huang, G., Xu, X., and . Researchers at Emory University School of Medicine found that a component of garlic oil, diallyl trisulfide, helps protect the heart after a heart attack and during heart surgery. One of the many other side effects of garlic during pregnancy is that it can also decrease the absorption capacity of iodine and cause hypothyroidism. 1993;32(4):623-626. A. 2006;20(6):504-510. Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576. J Antimicrob.Chemother. View abstract. It can cause side effects such as bad breath, heartburn, gas, and diarrhea. 2019 Jun 19. Garlic-induced hepatotoxicity following liver transplantation. Friedman, T., Shalom, A., and Westreich, M. Self-inflicted garlic burns: our experience and literature review. A., Breckler, L., Hale, J., Lehmann, H., Franklin, P., Lyons, G., Ching, S. Y., Mori, T. A., Barden, A., and Prescott, S. L. Supplementation with vitamins C, E, beta-carotene and selenium has no effect on anti-oxidant status and immune responses in allergic adults: a randomized controlled trial. View abstract. View abstract. What Happens If I Take Too Much Allicin? Vorberg G, Schneider B. Kaplan, B., Schewach-Millet, M., and Yorav, S. Factitial dermatitis induced by application of garlic. Sheela, C. G. and Augusti, K. T. Antidiabetic effects of S-allyl cysteine sulphoxide isolated from garlic Allium sativum Linn. Adler AJ, Holub BJ. Lack of personal hygiene is not the only cause of body odor, as consumption of garlic may result in it too (4). Transplant.Proc. 2009;(3):CD006206. Altern.Ther Health Med 2007;13(4):22-28. View abstract. Am J Emerg.Med 1997;15(5):548. Another potential risk occurs when you handle raw garlic to prepare it. J Med Chem. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. Oi, Y., Kawada, T., Shishido, C., Wada, K., Kominato, Y., Nishimura, S., Ariga, T., and Iwai, K. Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, and noradrenaline and adrenaline secretion in rats. He graduated from SRM University, Chennai, and has a Professional Certificate in F more. View abstract. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study. Zheng, W., Blot, W. J., Shu, X. O., Diamond, E. L., Gao, Y. T., Ji, B. T., and Fraumeni, J. F., Jr. A population-based case-control study of cancers of the nasal cavity and paranasal sinuses in Shanghai. Am J Gastroenterol. Results of a 3-year treatment with garlic extract on the reinfarction and mortality rate]. Carcinogenesis 1995;16:2649-52. Int J Cancer 1994;58:197-202. Aged garlic extract improves endothelial function in men with coronary artery disease. Hirsch, K., Danilenko, M., Giat, J., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D., Levy, J., and Sharoni, Y. View abstract. Orekhov AN, Pivovarova EM, and Tertov VV. Some studies have associated garlic and other members of the Allium family with a reduced risk of certain cancers. Mukherjee, M., Das, A. S., Mitra, S., and Mitra, C. Prevention of bone loss by oil extract of garlic (Allium sativum Linn.) Garlic might decrease how quickly the liver breaks down tacrolimus. Mukherjee, M., Das, A. S., Das, D., Mukherjee, S., Mitra, S., and Mitra, C. Role of oil extract of garlic (Allium sativum Linn.) Prostaglandins Leukot Essent Fatty Acids 1996;54(3):183-186. Arch Intern Med 1998;158:1189-94. These side effects are often worse with raw garlic. J R Coll Physicians Lond 1996;30:329-34. View abstract. 2005;57(5):623-630. Int.J Dermatol. Jabbari, A., Argani, H., Ghorbanihaghjo, A., and Mahdavi, R. Comparison between swallowing and chewing of garlic on levels of serum lipids, cyclosporine, creatinine and lipid peroxidation in Renal Transplant Recipients. London: Academic Press Ltd;1994. 8-16-2002;2:16. View abstract. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Imai J, Ide N, Nagae S, et al. Recent Pat Cardiovasc Drug Discov 2013;8(1):56-66. View abstract. Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men. Effect of dietary garlic (Allium Sativum) on the blood pressure in humans--a pilot study. Life Sci 1998;62:71-7. You WC, Zhang L, Gail MH, et al. Ann Intern Med 1993;119:599-605. Having mushrooms, basil, or water with garlic may also help (. Levi, F., Franceschi, S., Negri, E., and La Vecchia, C. Dietary factors and the risk of endometrial cancer. ", Kew Science, Plants of the World Online: "Allium sativum L.", L. Bayan et al., Avicenna Journal of Phytomedicine, "Garlic: a review of potential therapeutic effects. Lei, Y. P., Chen, H. W., Sheen, L. Y., and Lii, C. K. Diallyl disulfide and diallyl trisulfide suppress oxidized LDL-induced vascular cell adhesion molecule and E-selectin expression through protein kinase A- and B-dependent signaling pathways. Xiao, D., Pinto, J. T., Soh, J. W., Deguchi, A., Gundersen, G. G., Palazzo, A. F., Yoon, J. T., Shirin, H., and Weinstein, I. Curr.Med Res Opin. Steiner M, Khan AH, Holbert D, Lin RI. Mechanisms of garlic induced pulmonary vasorelaxation: role of allicin. View abstract. View abstract. A. 2016;32(1):33-40. Mechanism of antioxidation, inhibiting carcinogenesis and modification of LDL of aged garlic extract. Indian J Pathol.Microbiol. Garlic may interact with medications such as blood thinners. The Cleveland Clinic also identified garlic as a potential trigger for headaches. View abstract. Dietary intake of garlic and other Allium vegetables and breast cancer risk in a prospective study of postmenopausal women. 2011;38(3):280-282. Garlic oil has also been found to be protective against cardiomyopathy, a type of chronic heart disease that is the leading cause of death among diabetes patients. Bhuvaneswari, V., Abraham, S. K., and Nagini, S. Combinatorial antigenotoxic and anticarcinogenic effects of tomato and garlic through modulation of xenobiotic-metabolizing enzymes during hamster buccal pouch carcinogenesis. It can also cause heartburn, upset stomach, and diarrhea. In this case, you should see a doctor. View abstract. Am J Epidemiol. Br J Pharmacol 2008;154:1691-700. Tanaka, S., Haruma, K., Kunihiro, M., Nagata, S., Kitadai, Y., Manabe, N., Sumii, M., Yoshihara, M., Kajiyama, G., and Chayama, K. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study. Association and mechanism of garlic consumption with gastrointestinal cancer risk: A systematic review and meta-analysis. Journal of Medical Council of Islamic Republic of Iran (J MED COUNC ISLAMIC REPUB IRAN) 2005;23(3):319. View abstract. Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. This could decrease the effects of some medications used for HIV/AIDS. View abstract. Kweon, S., Park, K. A., and Choi, H. Chemopreventive effect of garlic powder diet in diethylnitrosamine-induced rat hepatocarcinogenesis. View abstract. View abstract. 2020;34(11):2953-2962. Common side effects (especially when eating raw garlic) may include: unpleasant breath or body odor; heartburn, burning in your mouth or throat; nausea, View abstract. Markowitz JS, Devane CL, Chavin KD, et al. Ajoene in the topical short-term treatment of tinea cruris and tinea corporis in humans. Qureshi AA, Din ZZ, Abuirmeileh N, et al. View abstract. View abstract. 12-6-2006;108(3):385-394. 2003;85(1):139-144. View abstract. 2007;25(4):164-168. Effects of garlic consumption on plasma and erythrocyte antioxidant parameters in elderly subjects. The effects of ginkgo and garlic on warfarin use. View abstract. Certain observational studies have also stated that taking garlic orally can cause heartburn and nausea (6). J Antimicrob.Chemother. Pushing the Envelope of Nutrition Support: Complementary Therapies. 1997;66(2):398-405. Hussain, S. P., Jannu, L. N., and Rao, A. R. Chemopreventive action of garlic on methylcholanthrene-induced carcinogenesis in the uterine cervix of mice. View abstract. Kianoush, S., Balali-Mood, M., Mousavi, S. R., Moradi, V., Sadeghi, M., Dadpour, B., Rajabi, O., and Shakeri, M. T. Comparison of therapeutic effects of garlic and d-Penicillamine in patients with chronic occupational lead poisoning. A historical perspective on garlic and cancer. Kenzelmann R, Kade F. Limitation of the deterioration of lipid parameters by a standardized garlic-ginkgo combination product. View abstract. Amirsalari S, Behboodi Moghadam Z, Taghizadeh Z, et al. Am.J.Clin.Nutr. 2008;22(10):1372-1379. Bradley R, Endres J, Hockenberry D, and et al. Das, I., Khan, N. S., and Sooranna, S. R. Potent activation of nitric oxide synthase by garlic: a basis for its therapeutic applications. Garlic contains a compound called allicin, which can J Ayub.Med Coll.Abbottabad. Risk factors for multiple myeloma: a hospital-based case-control study in Northwest China. 2017;42(5):646-648. If you have an upset stomach after eating garlic, you can try eating bland foods such as rice, bananas or bread. Int J Cancer 4-1-1994;57(1):38-46. View abstract. Garlic for peripheral arterial occlusive disease (Cochrane Review). Handb.Exp.Pharmacol. Pedraza-Chaverri, J., Maldonado, P. D., Medina-Campos, O. N., Olivares-Corichi, I. M., Granados-Silvestre, M. A., Hernandez-Pando, R., and Ibarra-Rubio, M. E. Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes. Therefore, those who already have the problem of bad breath should not eat garlic too much. View abstract. bland foods such as rice, bananas or bread, National Center for Complementary and Integrative Health: "Garlic", Consumer Reports: "The Health Benefits of Garlic", Cleveland Clinic: "6 Surprising Ways Garlic Boosts Your Health", Mayo Clinic: "Herbal Supplements and Heart Medicines May Not Mix". Hoshino, T et al. Deutsche Apotheker Zeitung 1989;129(28 suppl 15):16-17. 1991;21(2):497-502. Indian J Exp Biol 1992;30(6):523-526. Izzo, Angelo A, and Edzard Ernst. Eur J Obstet Gynecol Reprod Biol 2001;99:201-6.. View abstract. View abstract. J Nutr.Biochem. Mitchell, J. C. Contact sensitivity to garlic (Allium). Contact Dermatitis 2002;47(1):48. WebThe Effects of Eating Too Much Garlic on Digestion. View abstract. Meher S, Duley L. Garlic for preventing pre-eclampsia and its complications. Turner, B., Molgaard, C., and Marckmann, P. Effect of garlic (Allium sativum) powder tablets on serum lipids, blood pressure and arterial stiffness in normo-lipidaemic volunteers: a randomised, double-blind, placebo-controlled trial. J Ocul.Pharmacol.Ther 1999;15(1):9-17. Allium vegetables and reduced risk of stomach cancer. Vopr.Onkol. Garlic has been used safely for up to 7 years. Allium vegetables and risk of prostate cancer: evidence from 132,192 subjects. View abstract. Ide N, Nelson AB, and Lau BHS. View abstract. Its health action comes from the enzymes and unique compounds that it contains. Effect of supplementation with garlic oil on activity of Th1 and Th2 lymphocytes from rats. However, if you choose to take a supplement, you may want to exercise caution and use only the indicated amount. View abstract. According to National Center for Complementary and Integrated Health (NCCIH), there are limited studies on garlic. Acta Diabetol. Mader FH. 2009;23(4):513-518. Gardner CD, Chatterjee L, and Carlson J. Effect of cooking on garlic (Allium sativum l.) Antiplatelet activity and thiosulfinates content. Garlic may cause gastrointestinal discomfort. J Ethnopharmacol. J Nutr 1983;113:1746-55. 2009;89(1):257-264. Pharm.Res 1992;9(12):1668-1670. Fernandez-Vozmediano JM, Armario-Hita JC, Manrique-Plaza A. Allergic contact dermatitis from diallyl disulfide. Effects of garlic supplementation on oxidative stress and antioxidative capacity biomarkers: A systematic review and meta-analysis of randomized controlled trials. Rance, F. and Dutau, G. Labial food challenge in children with food allergy. View abstract. Lachter, J., Babich, J. P., Brookman, J. C., and Factor, A. Y. Garlic: a way out of work. Nutr.Cancer 1990;13(3):201-207. Seitan Nutrition: Benefits, Side Effects, 14 Serious Side Effects Of Olive Oil You Should Know About, 14 Side Effects Of Eating Too Many Bananas, Flax Seed Side Effects: 6 Ways It May Cause Harm, 14 Health Benefits Of Artichoke, Nutrition, & Side Effects, Health Benefits Of Garlic Oil, Side Effects, And How To Use It. Below we give you a list of garlic recipes that are good for your health during this delicate time. How much garlic is toxic? View abstract. U.S. STD Cases Increased During COVIDs 2nd Year, Pesticide in Produce: See the Latest Dirty Dozen, Having A-Fib Might Raise Odds for Dementia, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. View abstract. 2020;20(1):132. Is garlic also beneficial to a fatty liver? J Med Food 2006;9(4):537-544. View abstract. Symptoms might include: nausea. When You Shouldnt Eat Garlic 2001;10(2):137-165. Russell, J. E. Chinese complementary therapy for stress causing bilateral chemical burns to the feet. 1995;34(4):278-279. Cochrane.Database.Syst.Rev. Lembo, G., Balato, N., Patruno, C., Auricchio, L., and Ayala, F. Allergic contact dermatitis due to garlic (Allium sativum). Arzneimittelforschung 1992;42:1223-7. 30-40. View abstract. View abstract. 1999;141(2):391-392. Klin.Med (Mosk) 2001;79(11):55-58. 2015;28(3):414-23. Clin Res Hepatol Gastroenterol 2012;36(6):e134. Stop using garlic and call your healthcare provider at once if you have: redness, swelling, or blistering (when applied to the skin); or. Consuming garlic too frequently can cause you to have bad breath. View abstract. View abstract. View abstract. Groppo, F. C., Ramacciato, J. C., Motta, R. H., Ferraresi, P. M., and Sartoratto, A. Antimicrobial activity of garlic against oral streptococci. Efendy JL, Simmons DL, Campbell GR, Campbell JH. 1988;71(5):248-252. Lee, E. K., Chung, S. W., Kim, J. Y., Kim, J. M., Heo, H. S., Lim, H. A., Kim, M. K., Anton, S., Yokozawa, T., and Chung, H. Y. Allylmethylsulfide Down-Regulates X-Ray Irradiation-Induced Nuclear Factor-kappaB Signaling in C57/BL6 Mouse Kidney. 2004;87(10):1156-1161. Reinhart, K. M., Coleman, C. I., Teevan, C., Vachhani, P., and White, C. M. Effects of garlic on blood pressure in patients with and without systolic hypertension: a meta-analysis. 2006;136(3 Suppl):803S-805S. 2020. 2008;42(12):1766-1771. 2001;67(1):475-480. Reduction in elevated blood lipids in hospitalised patients by a standardised garlic preparation. View abstract. View abstract. View abstract. Int J Mol.Med 2002;9(6):641-643. Bruynzeel DP. View abstract. Thamburan, S., Klaasen, J., Mabusela, W. T., Cannon, J. F., Folk, W., and Johnson, Q. Tulbaghia alliacea phytotherapy: a potential anti-infective remedy for candidiasis. Garlic has most often been used by adults in doses of 2400 mg by mouth daily for 12 months. In vitro synergism of concentrated allium sativum extract and amphotericin B against cryptococcus neoformans. View abstract. Mice that received this component after a heart attack had 61% less damage to the affected cardiac tissue than untreated mice. [Epub ahead of print] View abstract. Large amounts of garlic might interfere with blood-thinning medications. Evidence Report/Technology Assessment No. Su, Q. S., Tian, Y., Zhang, J. G., and Zhang, H. Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity. View abstract. View abstract. 1990;68(2):163-169. 1983;23(5):700-702. Urol Clin North Am 2000;27:157-62. It has been found that excessive ingestion of garlic can lead to a condition called hyphema, which refers to bleeding inside the eye chamber the space between the iris and the cornea (16). Suppression of LDL oxidation by garlic. View abstract. Isr.Med Assoc J 2003;5(9):637-640. Arch Oral Biol. Sangouni AA, Alizadeh M, Jamalzehi A, Parastouei K. Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. Sunter WH. View abstract. How long does garlic stay in your system? Moriguchi T, Saito H, Nishiyama N. Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse. It can cause side effects such as bad breath, heartburn, gas, and diarrhea. View abstract. WebMD does not provide medical advice, diagnosis or treatment. Huang, J., Frohlich, J., and Ignaszewski, A. P. The impact of dietary changes and dietary supplements on lipid profile. 1-15-1993;137(2):155-165. Cancer Res 10-15-2003;63(20):6825-6837. Get emergency medical help if you have any of these signs of an allergic reaction while taking garlic: hives; difficult breathing; swelling of your face, lips, tongue, or throat. 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